Upon successful completion of the course, the student should:

• have of global perspective of interdisciplinary issues (biology, materials science, chemistry, and engineering) involved in biomaterials including bioplastics.
• know how to design, synthesize, evaluate, and analyze biomaterials.

The skills that the student is expected to develop upon successful completion of the course are:

• Ability to describe the various biomaterials including bioplastics.
• Ability to design, synthesize, evaluate, and analyze biomaterials.

• Critical thinking and analysis.
• Familiarization with biomaterials literature.

1. Introduction to biomaterials, biological response to biomaterials, types of biomaterials,
2. Processing and testing of biomaterials, important properties of biomaterials
3. Polymers and hydrogels, smart polymers
4. Chemical structure of biomaterials: crystal structure, point defect and diffusion of metals and ceramics,
5. Structure and synthesis of polymers, methods of polymerization, copolymer, material characterization techniques, X-ray diffraction.
6. Physical properties of biomaterials: crystallinity, linear, planar and volume defects, polymer crystallinity, thermal transitions of crystalline.
7. Mechanical properties of biomaterials: mechanical testing, hardness impact tests, fracture fatigue).
8. Degradation of biomaterials: corrosion/degradation of metals and ceramics, corrosion control, degradation of polymers, biodegradable materials.
9. Surface properties of biomaterials: Surface modification techniques, biological surface modification techniques, surface properties.
10. Biocompatibility, Biological testing of biomaterials
11. Proteins on biomaterials,
12. Non-fouling surfaces, biofilm
13. Biological response to biomaterials, inflammation and immunity

Assessment Method

• Αναστασοπούλου, Ι., Δρίτσα, Β., Θεοφανίδης, Θ., Υφαντής, Δ., Υφαντής, Κ., 2015. Βιοϋλικά - Εφαρμογές. [ηλεκτρ. βιβλ.] Αθήνα:Σύνδεσμος Ελληνικών Ακαδημαϊκών Βιβλιοθηκών. Διαθέσιμο στο: hdl.handle.net/11419/3635
• Ratner, B. D.; Hoffman, A. S.; Schoen, F. J.; Lemons, J. E., 3rd Eds, Biomaterials Science: An Introduction to Materials in Medicine, Elsevier Academic Press, 2012.